SHIFT 45+ Max
A two-tier women's wellness gummy line
built on Tongnan lemon pectin · Core & Pro variants
Dear Miss Yang,
We are developing a premium women's wellness supplement — SHIFT 45+ Max — for the United States and European Union markets. The product targets women aged 45 and above who are navigating the peri-menopausal and menopausal transition.
After studying your Mengxiaotai (檬小泰) product portfolio in detail, we have chosen Mengtai as our preferred manufacturing partner. Your vertical integration with Tongnan lemon — one of the world's three premier lemon-growing regions — gives this product a foundation no other supplier in Asia can match.
We are launching as two product variants in a single line — SHIFT 45+ Core (2 gummies/day, mass-market funnel) and SHIFT 45+ Pro (3 gummies/day, full clinical dose for the premium-tier customer). Both variants share the same flavor profiles and the same hero ingredients — they differ in the dose of select supporting actives. Below is the complete dual-variant specification along with ten critical questions.
Section IProject Overview · Two SKU Variants
| Item | SHIFT 45+ Core | SHIFT 45+ Pro |
|---|---|---|
| Brand owner | Sunside Sdn Bhd (Malaysia) | |
| Target market | USA + European Union (women aged 45+, peri-menopause / menopause) | |
| Format | Vegan pectin gummy candy | |
| Daily serving | 2 gummies per day (both with breakfast) | 3 gummies per day (2 morning + 1 evening) |
| Bottle size | 60 × 2g = 120g per bottle | 90 × 2g = 180g per bottle |
| Supply period | 30 days | 30 days |
| Positioning | Mass-market everyday wellness | Full-clinical premium tier |
| Volume mix (Year 1) | ~75% of total volume | ~25% of total volume |
| Flavor count | Both variants ship in 2 flavors: Lemon-Ginger Vegan · Lemon-Blueberry | |
| Allergen requirements | Vegan Soy-free Gluten-free Dairy-free Honey-free Non-GMO | |
| Shelf life target | 18 months minimum at 25°C / 60% RH | |
| Annual volume target | ~8,000 bottles Y1 · ~20,000 Y2 (~25% of mix) | ~25,000 Pro Kits Y1 · ~60,000 Y2 (~75% of mix) |
Section IIThree Distinct Gummy Formulas
The product line uses three unique gummy formulations. Both flavors (Lemon-Ginger Vegan + Lemon-Blueberry) apply to all three formulations — so the manufacturing run produces 6 unique gummy SKUs total (3 formulas × 2 flavors).
| Formula | Used In | Daily Intake | Time of Day |
|---|---|---|---|
| Formula ① Core Gummy | Core variant | 2 gummies (identical) | Both with breakfast |
| Formula ② Pro AM Gummy | Pro variant | 2 gummies (identical) | Both with breakfast |
| Formula ③ Pro PM Gummy | Pro variant | 1 gummy | With dinner |
Formula ① Core Gummy — All 19 actives compressed · 2 per day with breakfast
The Core variant is the all-in-one morning ritual. Both gummies share the same formula. Take 2 with breakfast.
| # | Ingredient | Per Gummy | Daily Total (×2) | Source / Patent |
|---|---|---|---|---|
| i | Berberine Phytosome | 550 mg | 1,100 mg | Indena Berbevis® |
| ii | S-equol from Kudzu Root | 5 mg | 10 mg | Pueraria lobata × Lactococcus 20-92, non-soy |
| iii | D-chiro Inositol (concentrated) | 150 mg | 300 mg | Pharmaceutical grade |
| iv | Saffron Extract | 14 mg | 28 mg | Pharmactive Affron® |
| v | Ashwagandha Root | 50 mg | 100 mg | Ixoreal KSM-66® |
| vi | Alpha-Lipoic Acid (R-form) | 100 mg | 200 mg | R-ALA preferred |
| vii | Apple Cider Vinegar powder | 250 mg | 500 mg | Bragg-equivalent, 5% AA |
| viii | Cinnamon (Ceylon, low-coumarin) | 75 mg | 150 mg | Sabinsa Cinnulin PF® |
| ix | EGCG (decaf green tea) | 50 mg | 100 mg | Taiyo Sunphenon® 90DCF |
| x | Chromium picolinate | 100 mcg | 200 mcg | Nutrition 21 Chromax® |
| xi | Vitamin D3 | 1,000 IU | 2,000 IU | DSM Quali-D® |
| xii | Vitamin K2 MK-7 | 45 mcg | 90 mcg | NattoPharma MenaQ7® |
| xiii | Magnesium glycinate | 37.5 mg | 75 mg | Albion TRAACS® |
| xiv | Vitamin B6 P-5-P | 2.5 mg | 5 mg | Active form |
| xv | Folate 5-MTHF | 200 mcg | 400 mcg | Gnosis Quatrefolic® |
| xvi | 12-strain patented probiotic | 2.5 B CFU | 5 B CFU | Your pectin-coated FoodTalksTop30 |
| xvii | Lemon-pectin prebiotic | 100 mg | 200 mg | Your patented prebiotic |
| xviii | Edible lemon oil | 15 mg | 30 mg | Your China-exclusive license |
| xix | Vitamin C (NFC Tongnan lemon) | 50 mg | 100 mg | Your Tongnan lemon source |
Active mass per Core gummy: approximately 1.55 g · Format: 60 gummies per bottle (30-day supply)
Formula ② Pro AM Gummy — Metabolic stack · 2 per day with breakfast
The morning Pro gummy carries the metabolic engine — actives that perform best in daylight with food. Two gummies identical, both with breakfast.
| # | Ingredient | Per Gummy | Daily AM Total (×2) | Source / Patent |
|---|---|---|---|---|
| i | Berberine Phytosome | 550 mg | 1,100 mg | Indena Berbevis® |
| ii | Inositol myo + d-chiro 40:1 (full clinical dose) | 1,000 mg | 2,000 mg | Pharmaceutical grade · full PCOS-grade |
| iii | Alpha-Lipoic Acid (R-form) | 100 mg | 200 mg | R-ALA preferred |
| iv | Apple Cider Vinegar powder | 250 mg | 500 mg | Bragg-equivalent |
| v | Cinnamon (Ceylon) | 100 mg | 200 mg | Sabinsa Cinnulin PF® |
| vi | EGCG (decaf) | 100 mg | 200 mg | Taiyo Sunphenon® 90DCF |
| vii | Chromium picolinate | 100 mcg | 200 mcg | Nutrition 21 Chromax® |
| viii | Vitamin D3 | 1,000 IU | 2,000 IU | DSM Quali-D® |
| ix | Vitamin K2 MK-7 | 45 mcg | 90 mcg | NattoPharma MenaQ7® |
| x | Vitamin B6 P-5-P | 2.5 mg | 5 mg | Active form |
| xi | Folate 5-MTHF | 200 mcg | 400 mcg | Gnosis Quatrefolic® |
| xii | 12-strain probiotic (split) | 1.25 B CFU | 2.5 B CFU AM | Half daily dose AM |
| xiii | Lemon-pectin prebiotic (split) | 50 mg | 100 mg AM | Half AM |
| xiv | Vitamin C from Tongnan lemon (split) | 25 mg | 50 mg AM | Half AM |
Active mass per Pro AM gummy: approximately 1.70 g · Format: 60 gummies per AM bottle
Formula ③ Pro PM Gummy — Sleep + hormone + beauty stack · 1 per day with dinner
The evening Pro gummy carries the hot-flash, sleep, mood, and beauty-recovery actives — circadian-aligned with overnight thermoregulation, GABA pathway, and skin repair cycles. Single gummy taken with dinner.
| # | Ingredient | Per Gummy | Daily PM (×1) | Source / Patent |
|---|---|---|---|---|
| i | S-equol from Kudzu Root ⭐ | 10 mg | 10 mg | Pueraria lobata × Lactococcus 20-92 — non-soy |
| ii | Ashwagandha (KSM-66®) ⭐ | 100 mg | 100 mg | Ixoreal KSM-66® |
| iii | Saffron Extract (Affron®) ⭐ | 28 mg | 28 mg | Pharmactive Affron® |
| iv | Magnesium glycinate ⭐ (full PM dose) | 100 mg | 100 mg | Albion TRAACS® |
| v | Fermented Rice Bran Extract ⭐ (Pro-exclusive · skin elasticity + GABA sleep) | 100 mg | 100 mg | Tsuno PeptiBalance® / OryzaPlus® OR your in-house ferment (≥10% gamma-oryzanol). Positioned as skin-elasticity + GABA-pathway support, not a hot flash claim. |
| vi | Edible lemon oil (full PM) | 30 mg | 30 mg | Your China-exclusive license |
| vii | 12-strain probiotic (split) | 2.5 B CFU | 2.5 B CFU PM | Half daily dose PM |
| viii | Lemon-pectin prebiotic (split) | 100 mg | 100 mg PM | Half PM (overnight gut) |
| ix | Vitamin C from Tongnan lemon (split) | 50 mg | 50 mg PM | Half PM |
Active mass per Pro PM gummy: approximately 0.75 g · Format: 30 gummies per PM bottle
Berbevis® 1,100mg · Inositol myo+d-chiro 40:1 at 2,000mg · Kudzu S-equol 10mg (★ hot flash hero) · KSM-66® 100mg · Affron® 28mg (★ mood/sleep hero) · ALA 200mg · ACV 500mg · Cinnamon 200mg · EGCG 200mg · Chromium 200mcg · D3 2,000 IU · K2 90mcg · Magnesium glycinate 100mg · B6 5mg · Folate 400mcg · 5B CFU probiotic · 200mg prebiotic · 100mg Vit C · 30mg lemon oil · 100mg Fermented Rice Bran Extract (Pro-exclusive — skin + GABA)
D. Base Matrix (your standard, modified)
- Gelling base: lemon pectin (primary) + carrageenan (secondary)
- Sweeteners: stevia (Reb-M, fermented) + monk fruit + small allulose — please reduce maltitol and trehalose from your standard to achieve ≤ 2 g sugar per serving
- Acidulants: citric acid + sodium citrate
- Fat-soluble carrier: sunflower lecithin + MCT oil (for D3, K2, EGCG, ALA delivery)
- Coating: carnauba wax matte finish
- Color: only natural sources — turmeric + paprika oleoresin (Lemon-Ginger) or natural anthocyanin (Lemon-Blueberry)
- Strictly excluded: honey, gelatin, soy protein, artificial colors, artificial flavors, sucrose, gluten, dairy
Section IIITwo Flavor Profiles
Section IVPackaging Requirements
| Item | Core Variant | Pro Variant (AM/PM Kit) |
|---|---|---|
| Consumer-facing package | 1 HDPE bottle | 1 outer box containing 2 inner bottles (AM + PM) |
| Bottle 1 (Core / Pro AM) | HDPE matte 120g · 60 gummies × 2g | HDPE matte 120g · 60 AM gummies × 2g |
| Bottle 2 (Pro PM only) | — | HDPE matte 60g · 30 PM gummies × 2g |
| Outer box (Pro only) | — | Premium matte rigid box · sleeve with gold "AM ☀" + indigo "PM ☾" iconography |
| Premium upgrade option | Standard HDPE | Glass amber bottles (Year 2 variant) |
| Total gummy SKU count | 6 unique gummy SKUs at the factory level = 3 formulas (Core / Pro AM / Pro PM) × 2 flavors (Lemon-Ginger · Lemon-Blueberry) | |
| Total consumer SKU count | 4 consumer-facing SKUs = 2 Core (LG + LB) + 2 Pro Kits (LG + LB) | |
| Common requirements | Tamper-evident seal · desiccant pouch · export-ready labeling (US English nutrition facts + EU food-supplement-compliant claims) · separate label artwork per SKU | |
Section VTen Critical Questions
Please address each question in your written reply. The answers determine production feasibility, timeline, and pricing.
Imported patented ingredient sourcing
Can your factory import and use the following seven named-patent ingredients in our custom OEM batch?
- Indena Berbevis® (Italy)
- Pharmactive Affron® (Spain)
- Ixoreal KSM-66® (India)
- NattoPharma MenaQ7® (Norway)
- Gnosis Quatrefolic® (Italy)
- Sabinsa Cinnulin PF® (India / USA)
- Tsuno PeptiBalance® or OryzaPlus® — fermented rice bran extract (Japan, for Pro variant only)
If yes, please indicate price-per-kg or per-unit cost, plus any supplier-side minimum order quantity.
For Tsuno (Japan) specifically: if direct import is difficult, can you propose your own in-house fermented rice bran extract (yeast or lactic-acid fermented, standardized to ≥10% gamma-oryzanol)? Mengtai's existing fermentation infrastructure (probiotic + lemon pectin) suggests this is within your capability. Please advise on cost difference between Tsuno imported vs your in-house ferment.
Kudzu S-equol fermentation
Can your factory ferment kudzu root (Pueraria lobata) extract using Lactococcus 20-92 strain — similar to Otsuka's SE5-OH process — to produce S-equol at 10 mg per serving?
If your facility does not have this fermentation capability, can you source SE5-OH ingredient through a licensed supplier? This is our most critical ingredient — non-soy S-equol is the central brand differentiator of this product.
Probiotic strain recommendation
Among your 12 patented FoodTalksTop30 strains, which 1-3 strains have the strongest evidence for women aged 45+ peri-menopausal gut–immune–metabolic crossover? Please share strain names and recommended CFU distribution. Our target is 5 billion CFU per serving total.
Inositol 40:1 sourcing at 2g dose
Can you source pharmaceutical-grade inositol with the exact 40:1 myo-inositol to d-chiro-inositol ratio at 2,000 mg per serving? This is the bulkiest single active in the formula.
High-load gummy capacity across 3 formulas
Three distinct active loads:
- Core gummy: ~1.55 g actives per 2g gummy (78% active load)
- Pro AM gummy: ~1.70 g actives per 2g gummy (85% active load — highest)
- Pro PM gummy: ~0.85 g actives per 2g gummy (42% active load — lowest)
Can your high-load pectin gummy technology achieve all three densities? Pro AM is the highest-load — please confirm feasibility specifically at 85% active load. If not, propose the closest workable formulation.
Two bottle sizes + AM/PM kit packaging
Three bottle SKUs needed from your line:
- Core bottle: 120g (60 × 2g — your standard format)
- Pro AM bottle: 120g (60 × 2g — same as Core, but Pro AM formula)
- Pro PM bottle: 60g (30 × 2g — smaller bottle for single-gummy daily PM)
Plus: AM/PM Kit outer box for the Pro variant, containing both the Pro AM and Pro PM bottles. Please advise on:
- Can your factory produce all three bottle sizes (120g + 120g + 60g)?
- Outer kit-box capability — matte rigid sleeve, premium tier? Cost per kit-box?
- If outer box not possible, can the two bottles be banded together (shrink-wrap or paper sleeve)?
Alpha-Lipoic Acid stability
Alpha-Lipoic Acid 200 mg may have a sulfur note and stability concern in pectin gummy matrix over an 18-month shelf life. Has your factory worked with ALA in gummy formats before? Any preferred form (R-ALA versus racemic) or microencapsulation requirement?
Certificate of Analysis documentation
Please confirm that your factory can provide third-party CoA for every active ingredient per batch, covering:
- Identity (HPLC for botanicals, ICP-MS for minerals)
- Purity and heavy metals (lead, arsenic, cadmium, mercury under EU/US limits)
- Microbiological (total plate count, yeast/mold, pathogens)
- Active assay (% berberine, % isoflavones, etc.)
- Pesticide residues for botanical actives
- Allergen testing (soy / gluten / dairy / nut below detection limit)
- CoA available in English
Stability testing for 18-month shelf life
We require 18-month shelf life at 25°C / 60% RH storage. Please confirm that your factory can run accelerated stability testing (40°C / 75% RH for 6 months) to validate this. Critical parameters: probiotic CFU survival, vitamin D3 retention, K2 retention, and ALA stability.
Pricing, MOQ, and Lead Times — separate quotes for all 6 gummy SKUs
Please quote in USD, FOB Chongqing, with separate pricing for each of the 6 unique gummy SKUs:
- Core Lemon-Ginger · Core Lemon-Blueberry (Core variant, 60-ct bottle)
- Pro AM Lemon-Ginger · Pro AM Lemon-Blueberry (Pro AM bottle, 60-ct)
- Pro PM Lemon-Ginger · Pro PM Lemon-Blueberry (Pro PM bottle, 30-ct)
Plus quote for AM/PM Kit packaging (outer box for Pro variant — 2 bottles per kit).
(a) Sensory prototype — 50 bottles per gummy SKU × 6 SKUs = 300 bottles total: cost per SKU + lead time?
(b) Pilot batch — 500 bottles per gummy SKU × 6 SKUs = 3,000 bottles total: cost per bottle per SKU + MOQ + lead time?
(c) Production batch — Pro is the volume leader (~75% of mix, Core ~25%):
- Core: 3,000-5,000 bottles per flavor (Core LG + Core LB = 6,000-10,000 total)
- Pro AM: 10,000-14,000 bottles per flavor (Pro AM LG + Pro AM LB = 20,000-28,000 total)
- Pro PM: 10,000-14,000 bottles per flavor (Pro PM LG + Pro PM LB = 20,000-28,000 total · matches AM 1:1)
- AM/PM Kit boxes: 20,000-28,000 boxes (one box bundles 1 AM bottle + 1 PM bottle per Pro consumer SKU)
Cost per bottle per SKU + MOQ + lead time?
Payment terms: 30% deposit + 70% on shipment, or your standard terms?
Section VIRegulatory Documentation
Please confirm the availability of:
- ISO 9001 + ISO 22000 + HACCP + GMP certifications
- China food production license (SC certification)
- Export licenses for USA + European Union
- Vegan certification (or willingness to certify)
- Non-GMO Project compatibility, kosher / halal eligibility (kosher preferred for US retail entry)
- 1-year US FDA New Dietary Ingredient (NDI) eligibility per active
- European Union food supplement notification documentation (per country, as required)
Section VIIAggressive 30-Day Production Timeline
We are compressing the production timeline to 30 days from this RFQ to mass production. Please confirm your factory can meet this aggressive timeline. If the standard timeline at your factory is longer, please indicate what specific stage requires more time and propose realistic adjustments.
| Phase | Milestone | Target Duration |
|---|---|---|
| Week 1 | Receive written quote + answered questions + 50-bottle sample per SKU (4 SKUs = 200 bottles total) for sensory verification | 7 days |
| Week 2 | Sensory testing on our side · approve/iterate flavor + texture · sign mass production order | 7 days |
| Week 3 | Mass production run: ~10,000 Core (split 2 flavors) + ~3,000 Pro (split 2 flavors) = ~13,000 bottles total · in-line QA | 7 days |
| Week 4 | Final QA + packaging + air freight to US 3PL warehouse | 7 days |
Total: 4 weeks (30 days) from this RFQ to first commercial inventory landed at the US warehouse. First DTC sale fires end of Month 1.
This timeline assumes (a) all imported patented ingredients (Berbevis®, Affron®, KSM-66®, MenaQ7®, Quatrefolic®, Cinnulin PF®) can be pre-ordered Week 1 in parallel with sample production, (b) sensory sample iteration completes in a single round, and (c) your factory has open production-line capacity. Please confirm feasibility or counter-propose with the fastest realistic timeline your factory can commit to.
Section VIIINext Steps
If your factory can fully or partially deliver this product, please send us:
- Your written answers to the ten questions above
- An initial price quote — rough estimate is acceptable, we can refine later
- A sample of your closest existing gummy products (specifically NFC Lemon Juice Vitamin C Pectin Gummy + Probiotic Prebiotic Pectin Gummy) so we can verify base manufacturing quality before pilot
We're looking forward to building this partnership. Thank you for the detailed Mengxiaotai product card — your Tongnan lemon vertical is exactly the foundation we want for this product.
With kind regards,
中文版本 · Chinese Version
杨女士您好，
我们正在为美国 + 欧盟市场开发一款女性高端健康营养软糖 — SHIFT 45+ Max。产品面向 45 岁以上、正经历围绝经期 / 绝经期过渡的女性。
在仔细研究贵公司"檬小泰"的完整产品体系后，我们已选择貴厂作为首选制造合作伙伴。贵厂与铜南柠檬 (世界三大顶级柠檬产区之一) 的垂直整合，是亚洲任何其他供应商无法匹及的产品基础。
我们将以同一产品线下的两个变体上市 — SHIFT 45+ Core (每天 2 粒，大众市场漏斗) 与 SHIFT 45+ Pro (每天 3 粒，完整临床剂量，面向高端用户)。两个变体共享相同的口味方案和相同的核心成分 — 仅在部分辅助成分的剂量上有所不同。下方是完整双变体规格 + 10 个关键问题。
第一节项目总览 · 双 SKU 变体
| 项目 | SHIFT 45+ Core | SHIFT 45+ Pro |
|---|---|---|
| 品牌方 | Sunside Sdn Bhd (马来西亚) | |
| 目标市场 | 美国 + 欧盟 (45 岁以上女性，围绝经期 / 绝经期) | |
| 剂型 | 素食果胶软糖 | |
| 每日服用量 | 每天 2 粒 (早餐时一起服) | 每天 3 粒 (早 2 粒 + 晚 1 粒) |
| 瓶装规格 | 60 × 2g = 120g / 瓶 | 90 × 2g = 180g / 瓶 |
| 供应周期 | 30 天 | 30 天 |
| 定位 | 大众市场日常健康 | 完整临床剂量高端层 |
| 销量占比 (第一年) | ~75% 总销量 | ~25% 总销量 |
| 口味数量 | 两个变体均提供 2 个口味: 柠檬姜素食 · 柠檬蓝莓 | |
| 过敏原要求 | 纯素 无大豆 无麸质 无乳 无蜂蜜 非转基因 | |
| 保质期目标 | 25°C / 60%RH 条件下至少 18 个月 | |
| 年度采购量 | 第一年约 8,000 瓶 · 第二年约 20,000 瓶 (约 25% 组合) | 第一年约 25,000 Pro 套装 · 第二年约 60,000 套装 (约 75% 组合) |
第二节三种独立软糖配方
产品线使用三种独立的软糖配方。两个口味 (柠檬姜素食 + 柠檬蓝莓) 适用于所有三种配方 — 因此生产批次共需生产6 个独立软糖 SKU (3 种配方 × 2 个口味)。
| 配方 | 用于 | 每日服用量 | 时段 |
|---|---|---|---|
| 配方 ① Core 软糖 | Core 变体 | 2 粒 (相同) | 早餐时一起服 |
| 配方 ② Pro AM 软糖 | Pro 变体 | 2 粒 (相同) | 早餐时一起服 |
| 配方 ③ Pro PM 软糖 | Pro 变体 | 1 粒 | 晚餐时服 |
配方 ① Core 软糖 — 19 种活性压缩 · 每日 2 粒早餐时
Core 变体是"一站式晨间仪式"。两粒软糖配方相同。早餐时一起服。
| # | 成分 | 每粒 | 每日总量 (×2) | 来源 / 专利 |
|---|---|---|---|---|
| i | 小檗碱磷脂复合物 | 550 mg | 1,100 mg | Indena Berbevis® |
| ii | 来自葛根的 S-equol | 5 mg | 10 mg | 葛根 × Lactococcus 20-92，非大豆 |
| iii | D-chiro 肌醇 (浓缩) | 150 mg | 300 mg | 药用级 |
| iv | 藏红花提取物 | 14 mg | 28 mg | Pharmactive Affron® |
| v | 南非醉茄根 | 50 mg | 100 mg | Ixoreal KSM-66® |
| vi | α-硫辛酸 (R 型) | 100 mg | 200 mg | R-ALA 优先 |
| vii | 苹果醋粉 | 250 mg | 500 mg | Bragg 同等 |
| viii | 锡兰桂皮 (低香豆素) | 75 mg | 150 mg | Sabinsa Cinnulin PF® |
| ix | EGCG (脱咖啡因) | 50 mg | 100 mg | Taiyo Sunphenon® 90DCF |
| x | 吡啶甲酸铬 | 100 mcg | 200 mcg | Nutrition 21 Chromax® |
| xi | 维生素 D3 | 1,000 IU | 2,000 IU | DSM Quali-D® |
| xii | 维生素 K2 MK-7 | 45 mcg | 90 mcg | NattoPharma MenaQ7® |
| xiii | 甘氨酸镁 | 37.5 mg | 75 mg | Albion TRAACS® |
| xiv | 维生素 B6 (P-5-P) | 2.5 mg | 5 mg | 活性形式 |
| xv | 5-甲基四氢叶酸 | 200 mcg | 400 mcg | Gnosis Quatrefolic® |
| xvi | 12 株专利益生菌 | 25 亿 CFU | 50 亿 CFU | 贵厂果胶包衣 FoodTalksTop30 |
| xvii | 柠檬果胶益生元 | 100 mg | 200 mg | 贵厂专利 |
| xviii | 食用柠檬精油 | 15 mg | 30 mg | 贵厂中国独家许可 |
| xix | 维生素 C (铜南柠檬) | 50 mg | 100 mg | 贵厂铜南柠檬来源 |
Core 每粒有效成分质量: 约 1.55 g · 规格: 每瓶 60 粒 (30 天用量)
配方 ② Pro AM 软糖 — 代谢栈 · 每日 2 粒早餐时
早晨 Pro 软糖搭载代谢引擎 — 在日光与餐食中表现最佳的活性。两粒相同，早餐时服。
| # | 成分 | 每粒 | 每日 AM 总量 (×2) | 来源 / 专利 |
|---|---|---|---|---|
| i | 小檗碱磷脂复合物 | 550 mg | 1,100 mg | Indena Berbevis® |
| ii | 肌醇 myo + d-chiro 40:1 (完整临床剂量) | 1,000 mg | 2,000 mg | 药用级 · 完整 PCOS 级 |
| iii | α-硫辛酸 (R 型) | 100 mg | 200 mg | R-ALA 优先 |
| iv | 苹果醋粉 | 250 mg | 500 mg | Bragg 同等 |
| v | 锡兰桂皮 | 100 mg | 200 mg | Sabinsa Cinnulin PF® |
| vi | EGCG (脱咖啡因) | 100 mg | 200 mg | Taiyo Sunphenon® 90DCF |
| vii | 吡啶甲酸铬 | 100 mcg | 200 mcg | Nutrition 21 Chromax® |
| viii | 维生素 D3 | 1,000 IU | 2,000 IU | DSM Quali-D® |
| ix | 维生素 K2 MK-7 | 45 mcg | 90 mcg | NattoPharma MenaQ7® |
| x | 维生素 B6 P-5-P | 2.5 mg | 5 mg | 活性形式 |
| xi | 5-甲基四氢叶酸 | 200 mcg | 400 mcg | Gnosis Quatrefolic® |
| xii | 12 株益生菌 (分配) | 12.5 亿 CFU | 25 亿 CFU AM | 每日剂量一半 AM |
| xiii | 柠檬果胶益生元 (分配) | 50 mg | 100 mg AM | 一半 AM |
| xiv | 维生素 C (分配) | 25 mg | 50 mg AM | 一半 AM |
Pro AM 每粒有效成分质量: 约 1.70 g · 规格: 每 AM 瓶 60 粒
配方 ③ Pro PM 软糖 — 助眠 + 激素 + 美容栈 · 每日 1 粒晚餐时
傍晚 Pro 软糖搭载热潮红、助眠、情绪、美容修复活性 — 与昼夜节律对齐 (夜间体温调节、GABA 通路、皮肤修复周期)。每日 1 粒晚餐时服。
| # | 成分 | 每粒 | 每日 PM (×1) | 来源 / 专利 |
|---|---|---|---|---|
| i | 葛根 S-equol ⭐ | 10 mg | 10 mg | 葛根 × Lactococcus 20-92 — 非大豆 |
| ii | 南非醉茄 (KSM-66®) ⭐ | 100 mg | 100 mg | Ixoreal KSM-66® |
| iii | 藏红花 (Affron®) ⭐ | 28 mg | 28 mg | Pharmactive Affron® |
| iv | 甘氨酸镁 ⭐ (PM 完整剂量) | 100 mg | 100 mg | Albion TRAACS® |
| v | 发酵米糠提取物 ⭐ (Pro 独家 · 皮肤弹性 + GABA 助眠) | 100 mg | 100 mg | Tsuno PeptiBalance® / OryzaPlus® 或贵厂自有发酵 (γ-谷维素 ≥10%)。定位为皮肤弹性 + GABA 通路支持，不作热潮红声明。 |
| vi | 食用柠檬精油 (PM 完整) | 30 mg | 30 mg | 贵厂中国独家许可 |
| vii | 12 株益生菌 (分配) | 25 亿 CFU | 25 亿 CFU PM | 每日剂量一半 PM |
| viii | 柠檬果胶益生元 (分配) | 100 mg | 100 mg PM | 一半 PM (夜间肠道) |
| ix | 维生素 C (分配) | 50 mg | 50 mg PM | 一半 PM |
Pro PM 每粒有效成分质量: 约 0.75 g · 规格: 每 PM 瓶 30 粒
Berbevis® 1,100mg · 肌醇 myo+d-chiro 40:1 2,000mg · 葛根 S-equol 10mg (★ 热潮红明星) · KSM-66® 100mg · Affron® 28mg (★ 情绪 / 助眠明星) · ALA 200mg · ACV 500mg · 桂皮 200mg · EGCG 200mg · 铬 200mcg · D3 2,000 IU · K2 90mcg · 甘氨酸镁 100mg · B6 5mg · 叶酸 400mcg · 50 亿 CFU 益生菌 · 200mg 益生元 · 100mg 维生素 C · 30mg 柠檬精油 · 100mg 发酵米糠提取物 (Pro 独家 — 皮肤 + GABA)
D. 基质 (贵厂标准，含修改)
- 凝胶基底: 柠檬果胶 (主) + 卡拉胶 (副)
- 甜味剂: 甜菊糖苷 (Reb-M 发酵法) + 罗汉果苷 + 少量阿洛酮糖 — 请减少贵厂标准配方中麦芽糖醇 + 海藻糖用量，目标每份糖分 ≤ 2g
- 酸味剂: 柠檬酸 + 柠檬酸钠
- 脂溶性载体: 葵花卵磷脂 + MCT 油 (D3、K2、EGCG、ALA 输送载体)
- 涂层: 巴西棕榈蜡哑光面
- 色素: 仅天然来源 — 姜黄 + 红椒油树脂 (柠檬姜) 或天然花青素 (柠檬蓝莓)
- 严格不含: 蜂蜜、明胶、大豆蛋白、人工色素、人工香料、蔗糖、麸质、乳制品
第三节两种口味方案
第四节包装要求
| 项目 | Core 变体 | Pro 变体 (AM/PM 套装) |
|---|---|---|
| 消费者包装 | 1 个 HDPE 瓶 | 1 个外盒含 2 个内瓶 (AM + PM) |
| 瓶 1 (Core / Pro AM) | HDPE 哑光 120g · 60 粒 × 2g | HDPE 哑光 120g · 60 粒 AM × 2g |
| 瓶 2 (仅 Pro PM) | — | HDPE 哑光 60g · 30 粒 PM × 2g |
| 外盒 (仅 Pro) | — | 高端哑光硬盒 · 套筒带金色"AM ☀" + 靛蓝"PM ☾"图标 |
| 高端升级选项 | 标准 HDPE | 玻璃琥珀瓶 (第二年) |
| 软糖 SKU 总数 | 共 6 个独立软糖 SKU = 3 种配方 (Core / Pro AM / Pro PM) × 2 个口味 (柠檬姜 · 柠檬蓝莓) | |
| 消费者 SKU 总数 | 共 4 个消费者 SKU = 2 个 Core (柠檬姜 + 柠檬蓝莓) + 2 个 Pro 套装 (柠檬姜 + 柠檬蓝莓) | |
| 通用要求 | 防拆封封口 · 干燥剂 · 出口标签 (美国英文营养成分表 + 欧盟食品补充剂合规声明) · 每个 SKU 独立标签设计 | |
第五节10 个关键问题
请在回复中逐一答复以下问题。这些答复决定了生产可行性、时间表和价格。
进口专利成分采购
贵厂能否进口并在我们的定制 OEM 批次中使用以下 7 种指定专利成分?
- Indena Berbevis® (意大利)
- Pharmactive Affron® (西班牙)
- Ixoreal KSM-66® (印度)
- NattoPharma MenaQ7® (挪威)
- Gnosis Quatrefolic® (意大利)
- Sabinsa Cinnulin PF® (印度 / 美国)
- Tsuno PeptiBalance® 或 OryzaPlus® — 发酵米糠提取物 (日本，仅 Pro 变体)
如可以，请告知每公斤或每单位价格，以及供应商端的最低采购量。
关于日本 Tsuno 具体而言: 如直接进口困难，贵厂能否提议自有发酵米糠提取物 (酵母或乳酸菌发酵，标准化 γ-谷维素 ≥10%)? 贵厂现有的发酵基础设施 (益生菌 + 柠檬果胶) 表明这在贵厂能力范围内。请告知 Tsuno 进口与贵厂自有发酵的成本差。
葛根 S-equol 发酵
贵厂能否使用 Lactococcus 20-92 菌株 (类似大塚 Otsuka SE5-OH 工艺) 发酵葛根 (Pueraria lobata) 提取物，生产每份 10 mg 的 S-equol?
如贵厂没有此发酵能力，能否通过授权供应商采购 SE5-OH 成分? 这是最关键的成分 — 非大豆来源的 S-equol 是本产品的核心品牌差异化。
益生菌菌株推荐
在贵厂 12 种专利 FoodTalksTop30 菌株中，哪 1-3 株菌对 45+ 围绝经期女性"肠-免疫-代谢"交叉作用证据最充分? 请提供菌株名称和推荐 CFU 剂量分配。我们目标是每份共计 50 亿 CFU。
肌醇 40:1 比例 2g 剂量
贵厂能否采购药用级肌醇，精确按 40:1 myo / d-chiro 比例配置，每份 2,000 mg? 这是配方中体积最大的单一有效成分。
三种配方的高负载软糖容量
三种独立的有效成分负载:
- Core 软糖: 每 2g 软糖约 1.55 g 有效成分 (78% 负载)
- Pro AM 软糖: 每 2g 软糖约 1.70 g 有效成分 (85% 负载 — 最高)
- Pro PM 软糖: 每 2g 软糖约 0.85 g 有效成分 (42% 负载 — 最低)
贵厂高负载果胶软糖技术能否同时达到这三种密度? Pro AM 是最高负载 — 请特别确认 85% 有效成分负载的可行性。如不能，请提议最接近的可行配方。
两种瓶装规格 + AM/PM 套装包装
贵厂生产线需提供三种瓶装 SKU:
- Core 瓶: 120g (60 × 2g — 贵厂标准)
- Pro AM 瓶: 120g (60 × 2g — 与 Core 相同，但 Pro AM 配方)
- Pro PM 瓶: 60g (30 × 2g — 小瓶用于每日单粒 PM)
另: Pro 变体的 AM/PM 套装外盒，含 Pro AM 与 Pro PM 两瓶。请告知:
- 贵厂能否生产三种瓶装规格 (120g + 120g + 60g)?
- 外套装盒能力 — 哑光硬质套筒，高端层? 每套装盒成本?
- 如外盒不可行，能否将两瓶捆绑 (热缩膜或纸套)?
α-硫辛酸 (ALA) 稳定性
α-硫辛酸 200 mg 在果胶软糖基质中 18 个月保质期内可能存在硫味和稳定性问题。贵厂是否处理过 ALA 在软糖中的应用? 优先形式 (R-ALA 与外消旋) 或需要微胶囊化吗?
CoA 分析证书文件
请确认贵厂能为每批次的每种有效成分提供第三方分析证书 (CoA)，涵盖:
- 鉴定 (HPLC 用于植物，ICP-MS 用于矿物质)
- 纯度和重金属 (铅、砷、镉、汞 < EU/US 限量)
- 微生物学 (总菌落数、酵母 / 霉菌、致病菌)
- 有效物含量 (小檗碱百分比、异黄酮百分比等)
- 农药残留 (针对植物成分)
- 过敏原测试 (大豆 / 麸质 / 乳 / 坚果 < 检出限)
- 英文版 CoA
稳定性测试 (18 个月保质期)
我们要求在 25°C / 60%RH 储存条件下保质期 18 个月。请确认贵厂可以进行加速稳定性测试 (40°C / 75%RH × 6 个月) 来验证。关键参数: 益生菌 CFU 存活、维生素 D3 保留、K2 保留、ALA 稳定性。
价格、MOQ、交货时间 — 全部 6 个软糖 SKU 分别报价
请按美元 FOB 重庆报价，6 种独立软糖 SKU 分别报价:
- Core 柠檬姜 · Core 柠檬蓝莓 (Core 变体，60 粒装)
- Pro AM 柠檬姜 · Pro AM 柠檬蓝莓 (Pro AM 瓶，60 粒装)
- Pro PM 柠檬姜 · Pro PM 柠檬蓝莓 (Pro PM 瓶，30 粒装)
另请报价AM/PM 套装包装(Pro 变体的外盒 — 每套含 2 瓶)。
(a) 感官样品 — 每软糖 SKU 50 瓶 × 6 SKU = 共 300 瓶: 每 SKU 费用 + 交货时间?
(b) 试产批次 — 每软糖 SKU 500 瓶 × 6 SKU = 共 3,000 瓶: 每瓶每 SKU 价格 + MOQ + 交货时间?
(c) 量产批次 — Pro 为销量主导 (约 75% 组合，Core 约 25%):
- Core: 每口味 3,000-5,000 瓶 (Core 柠檬姜 + Core 柠檬蓝莓 = 共 6,000-10,000)
- Pro AM: 每口味 10,000-14,000 瓶 (Pro AM 柠檬姜 + Pro AM 柠檬蓝莓 = 共 20,000-28,000)
- Pro PM: 每口味 10,000-14,000 瓶 (Pro PM 柠檬姜 + Pro PM 柠檬蓝莓 = 共 20,000-28,000 · 与 AM 1:1 对等)
- AM/PM 套装盒: 20,000-28,000 盒 (每盒装 1 个 AM 瓶 + 1 个 PM 瓶，每个 Pro 消费者 SKU 一盒)
每瓶每 SKU 价格 + MOQ + 交货时间?
付款条款: 30% 定金 + 70% 出货前付清，或贵方标准条款?
第六节监管文件要求
请确认以下文件可用性:
- ISO 9001 + ISO 22000 + HACCP + GMP 认证
- 中国食品生产许可 (SC 证)
- 美国 + 欧盟出口许可证
- 素食认证 (或愿意申请认证)
- 非转基因项目兼容性，犹太洁食 / 清真资质 (美国零售优先犹太洁食)
- 1 年期美国 FDA 新膳食成分 (NDI) 资格文件 (每个有效成分)
- 欧盟食品补充剂通报文件 (如需按国家)
第七节30 天加速生产时间表
我们将生产时间表压缩为从本 RFQ 到量产 30 天。请确认贵厂能否达到此加速时间表。如贵厂标准时间表更长，请指明具体哪个阶段需要更多时间，并提出实际的调整方案。
| 阶段 | 里程碑 | 目标时长 |
|---|---|---|
| 第 1 周 | 收到贵厂书面报价 + 问题答复 + 每 SKU 50 瓶样品 (共 4 SKU = 200 瓶) 用于感官验证 | 7 天 |
| 第 2 周 | 我方感官测试 · 批准 / 调整口味与质地 · 签量产订单 | 7 天 |
| 第 3 周 | 量产批生产: 约 10,000 瓶 Core (分 2 口味) + 约 3,000 瓶 Pro (分 2 口味) = 共约 13,000 瓶 · 在线 QA | 7 天 |
| 第 4 周 | 最终 QA + 包装 + 空运至美国 3PL 仓库 | 7 天 |
总计: 4 周 (30 天)从本 RFQ 到首批商业库存到达美国仓库。Month 1 月底首次 DTC 销售。
此时间表假设: (a) 所有进口专利成分 (Berbevis®, Affron®, KSM-66®, MenaQ7®, Quatrefolic®, Cinnulin PF®) 可在第 1 周与样品生产并行预订, (b) 感官样品迭代单轮完成, (c) 贵厂有开放的生产线产能。请确认可行性，或反提议贵厂能承诺的最快实际时间表。
第八节下一步
如贵厂能完全或部分交付本产品，请发送以下内容:
- 上述 10 个问题的书面答复
- 初步报价 (粗略估算即可，后续可细化)
- 贵厂现有最接近的软糖产品样品 (具体: NFC 柠檬汁维生素 C 果胶软糖 + 益生菌益生元果胶软糖)，以便我们在承诺试产前验证贵厂基础生产质量
期待与贵厂建立长期合作伙伴关系。再次感谢贵公司提供的詳細"檬小泰"产品资料 — 贵厂的铜南柠檬垂直产业链正是我们想要的产品基础。
此致敬礼