SHIFT 45+ Max
A two-tier women's wellness gummy line
built on Tongnan lemon pectin · Core & Pro variants
Dear Miss Yang,
We are developing a premium women's wellness supplement — SHIFT 45+ Max — for the United States and European Union markets. The product targets women aged 45 and above who are navigating the peri-menopausal and menopausal transition.
After studying your Mengxiaotai (檬小泰) product portfolio in detail, we have chosen Mengtai as our preferred manufacturing partner. Your vertical integration with Tongnan lemon — one of the world's three premier lemon-growing regions — gives this product a foundation no other supplier in Asia can match.
We are launching as two product variants in a single line — SHIFT 45+ Core (2 gummies/day, mass-market funnel) and SHIFT 45+ Pro (3 gummies/day, full clinical dose for the premium-tier customer). Both variants share the same flavor profiles and the same hero ingredients — they differ in the dose of select supporting actives. Below is the complete dual-variant specification along with ten critical questions.
Section IProject Overview · Two SKU Variants
| Item | SHIFT 45+ Core | SHIFT 45+ Pro |
|---|---|---|
| Brand owner | Sunside Sdn Bhd (Malaysia) | |
| Target market | USA + European Union (women aged 45+, peri-menopause / menopause) | |
| Format | Vegan pectin gummy candy | |
| Daily serving | 2 gummies per day (both with breakfast) | 3 gummies per day (2 morning + 1 evening) |
| Bottle size | 60 × 2g = 120g per bottle | 90 × 2g = 180g per bottle |
| Supply period | 30 days | 30 days |
| Target retail (USD) | $69 (subscribe $55) | $89 (subscribe $71) |
| Positioning | Mass-market everyday wellness | Full-clinical premium tier |
| Volume mix (Year 1) | ~75% of total volume | ~25% of total volume |
| Flavor count | Both variants ship in 2 flavors: Lemon-Ginger Vegan · Lemon-Blueberry | |
| Allergen requirements | Vegan Soy-free Gluten-free Dairy-free Honey-free Non-GMO | |
| Shelf life target | 18 months minimum at 25°C / 60% RH | |
| Annual volume target | ~25,000 bottles Y1 · ~60,000 Y2 | ~8,000 bottles Y1 · ~20,000 Y2 |
Section IIFull Formula Core (2-gummy) and Pro (3-gummy) variants compared
Both variants share the same nineteen functional ingredients. The differences are concentrated in the inositol bulk active and three supporting ingredients (cinnamon, EGCG, magnesium) where the Pro variant restores the full clinical RCT dose. Please confirm sourcing capability and per-unit cost for each ingredient.
A. Hero Ingredients (clinical-trial dose-matched — both variants identical)
| # | Ingredient | Core (2G) | Pro (3G) | Required Source / Patent |
|---|---|---|---|---|
| i | Berberine Phytosome | 1,100 mg | 1,100 mg | Indena Berbevis® (Italy) — named patent required |
| ii | S-equol from Kudzu Root | 10 mg | 10 mg | Pueraria lobata fermented via Lactococcus 20-92 — non-soy required |
| iii | Inositol | 300 mg D-chiro | 2,000 mg myo+d-chiro 40:1 | Pharmaceutical grade · Pro restores full PCOS-grade dose |
| iv | Saffron Extract | 28 mg | 28 mg | Pharmactive Affron® (Spain) — named patent required |
| v | Ashwagandha Root Extract | 100 mg | 100 mg | Ixoreal KSM-66® (India) — named patent required |
| vi | Alpha-Lipoic Acid (R-ALA preferred) | 200 mg | 200 mg | Stability flagged — see Question 7 |
B. Metabolic & Structural Support
| # | Ingredient | Core (2G) | Pro (3G) | Source / Patent |
|---|---|---|---|---|
| vii | Apple Cider Vinegar powder | 500 mg | 500 mg | Bragg-equivalent acetic acid, 5% AA |
| viii | Cinnamon extract (Ceylon, low-coumarin) | 150 mg | 200 mg | Sabinsa Cinnulin PF® |
| ix | EGCG (decaffeinated green tea) | 100 mg | 200 mg | Taiyo Sunphenon® 90DCF |
| x | Chromium picolinate | 200 mcg | 200 mcg | Nutrition 21 Chromax® |
| xi | Vitamin D3 (cholecalciferol) | 2,000 IU | 2,000 IU | DSM Quali-D® |
| xii | Vitamin K2 MK-7 | 90 mcg | 90 mcg | NattoPharma MenaQ7® |
| xiii | Magnesium glycinate (elemental) | 75 mg | 100 mg | Albion TRAACS® |
| xiv | Vitamin B6 (P-5-P active form) | 5 mg | 5 mg | Pyridoxal-5-phosphate |
| xv | Folate 5-MTHF | 400 mcg DFE | 400 mcg DFE | Gnosis Quatrefolic® |
C. Mengtai Exclusive (your existing capability — both variants identical)
| # | Ingredient | Core (2G) | Pro (3G) | Notes |
|---|---|---|---|---|
| xvi | 12-strain patented probiotic | 5 billion CFU | 5 billion CFU | Your pectin-coated FoodTalksTop30 panel (98% intestinal survival). Please recommend best 1-3 strains for women 45+. |
| xvii | Lemon-pectin prebiotic | 200 mg | 200 mg | Your patented lemon-pectin prebiotic |
| xviii | Natural edible lemon oil | 30 mg | 30 mg | Your China-exclusive lemon oil license — "Tongnan terroir signature" |
| xix | Vitamin C (from NFC Tongnan lemon) | 100 mg | 100 mg | From your existing Tongnan lemon source |
D. Pro-Exclusive Differentiator (Pro variant only — beauty + hot flash booster)
| # | Ingredient | Core (2G) | Pro (3G) | Required Source |
|---|---|---|---|---|
| xx | Fermented Rice Bran Extract (≥10% gamma-oryzanol) | — | 200 mg | Japanese Tsuno PeptiBalance® or OryzaPlus® preferred. If not available, please propose your in-house fermented rice bran (yeast or lactic acid fermented) — see Question 1 for sourcing. |
Rationale for Pro-only addition: fermented rice bran extract adds three documented mechanisms — gamma-oryzanol (Japan-approved Foshu claim for menopause hot flashes, stacks with our S-equol), GABA (sleep synergy with KSM-66 + saffron), and tocotrienols/ferulic acid (skin elasticity for beauty-from-within positioning). This is the central reason a customer upgrades from Core to Pro.
Core (2 × 2g gummies): approximately 3.1 g actives total — ~1.55 g actives per gummy
Pro (3 × 2g gummies): approximately 5.0 g actives total — ~1.67 g actives per gummy (includes 200mg FRBE)
Both are high-load pectin formulations. Please address feasibility in Question 5 below.
D. Base Matrix (your standard, modified)
- Gelling base: lemon pectin (primary) + carrageenan (secondary)
- Sweeteners: stevia (Reb-M, fermented) + monk fruit + small allulose — please reduce maltitol and trehalose from your standard to achieve ≤ 2 g sugar per serving
- Acidulants: citric acid + sodium citrate
- Fat-soluble carrier: sunflower lecithin + MCT oil (for D3, K2, EGCG, ALA delivery)
- Coating: carnauba wax matte finish
- Color: only natural sources — turmeric + paprika oleoresin (Lemon-Ginger) or natural anthocyanin (Lemon-Blueberry)
- Strictly excluded: honey, gelatin, soy protein, artificial colors, artificial flavors, sucrose, gluten, dairy
Section IIITwo Flavor Profiles
Section IVPackaging Requirements
| Item | Core (2G) | Pro (3G) |
|---|---|---|
| Bottle | HDPE matte 120g (60 × 2g) | HDPE matte 180g (90 × 2g) — custom |
| Premium upgrade option | Standard HDPE | Glass amber bottle variant for Year 2 |
| Total SKU count | 4 SKUs total = 2 variants × 2 flavors (Core Lemon-Ginger · Core Lemon-Blueberry · Pro Lemon-Ginger · Pro Lemon-Blueberry) | |
| Common requirements | Tamper-evident seal · desiccant pouch · export-ready labeling (US English nutrition facts + EU food-supplement-compliant claims) · separate label artwork per SKU | |
Section VTen Critical Questions
Please address each question in your written reply. The answers determine production feasibility, timeline, and pricing.
Imported patented ingredient sourcing
Can your factory import and use the following seven named-patent ingredients in our custom OEM batch?
- Indena Berbevis® (Italy)
- Pharmactive Affron® (Spain)
- Ixoreal KSM-66® (India)
- NattoPharma MenaQ7® (Norway)
- Gnosis Quatrefolic® (Italy)
- Sabinsa Cinnulin PF® (India / USA)
- Tsuno PeptiBalance® or OryzaPlus® — fermented rice bran extract (Japan, for Pro variant only)
If yes, please indicate price-per-kg or per-unit cost, plus any supplier-side minimum order quantity.
For Tsuno (Japan) specifically: if direct import is difficult, can you propose your own in-house fermented rice bran extract (yeast or lactic-acid fermented, standardized to ≥10% gamma-oryzanol)? Mengtai's existing fermentation infrastructure (probiotic + lemon pectin) suggests this is within your capability. Please advise on cost difference between Tsuno imported vs your in-house ferment.
Kudzu S-equol fermentation
Can your factory ferment kudzu root (Pueraria lobata) extract using Lactococcus 20-92 strain — similar to Otsuka's SE5-OH process — to produce S-equol at 10 mg per serving?
If your facility does not have this fermentation capability, can you source SE5-OH ingredient through a licensed supplier? This is our most critical ingredient — non-soy S-equol is the central brand differentiator of this product.
Probiotic strain recommendation
Among your 12 patented FoodTalksTop30 strains, which 1-3 strains have the strongest evidence for women aged 45+ peri-menopausal gut–immune–metabolic crossover? Please share strain names and recommended CFU distribution. Our target is 5 billion CFU per serving total.
Inositol 40:1 sourcing at 2g dose
Can you source pharmaceutical-grade inositol with the exact 40:1 myo-inositol to d-chiro-inositol ratio at 2,000 mg per serving? This is the bulkiest single active in the formula.
High-load gummy capacity for both variants
Both variants are high-load pectin formulations:
- Core: ~1.55 g actives per 2g gummy (78% active load)
- Pro: ~1.60 g actives per 2g gummy (80% active load)
Can your high-load pectin gummy technology achieve both densities? If not, please propose the closest workable formulation.
Two bottle sizes
We need two bottle SKUs from your line: Core at 120g (60 × 2g — your standard) and Pro at 180g (90 × 2g — custom). Is the 180g bottle feasible on your production line? Per-bottle cost difference vs your 120g standard?
Alpha-Lipoic Acid stability
Alpha-Lipoic Acid 200 mg may have a sulfur note and stability concern in pectin gummy matrix over an 18-month shelf life. Has your factory worked with ALA in gummy formats before? Any preferred form (R-ALA versus racemic) or microencapsulation requirement?
Certificate of Analysis documentation
Please confirm that your factory can provide third-party CoA for every active ingredient per batch, covering:
- Identity (HPLC for botanicals, ICP-MS for minerals)
- Purity and heavy metals (lead, arsenic, cadmium, mercury under EU/US limits)
- Microbiological (total plate count, yeast/mold, pathogens)
- Active assay (% berberine, % isoflavones, etc.)
- Pesticide residues for botanical actives
- Allergen testing (soy / gluten / dairy / nut below detection limit)
- CoA available in English
Stability testing for 18-month shelf life
We require 18-month shelf life at 25°C / 60% RH storage. Please confirm that your factory can run accelerated stability testing (40°C / 75% RH for 6 months) to validate this. Critical parameters: probiotic CFU survival, vitamin D3 retention, K2 retention, and ALA stability.
Pricing, MOQ, and Lead Times — both variants separately
Please quote in USD, FOB Chongqing, with separate pricing for Core and Pro at each batch size. Total SKU count is 4 (2 variants × 2 flavors).
(a) Sensory prototype — 50 bottles per SKU × 4 SKUs = 200 bottles total: cost per SKU + lead time?
(b) Pilot batch — 500 bottles per SKU × 4 SKUs = 2,000 bottles total: cost per bottle per SKU + MOQ + lead time?
(c) Production batch — Core: 5,000-7,000 per flavor (10,000-14,000 total); Pro: 2,000-3,000 per flavor (4,000-6,000 total). Cost per bottle per SKU + MOQ + lead time?
Payment terms: 30% deposit + 70% on shipment, or your standard terms?
Section VIRegulatory Documentation
Please confirm the availability of:
- ISO 9001 + ISO 22000 + HACCP + GMP certifications
- China food production license (SC certification)
- Export licenses for USA + European Union
- Vegan certification (or willingness to certify)
- Non-GMO Project compatibility, kosher / halal eligibility (kosher preferred for US retail entry)
- 1-year US FDA New Dietary Ingredient (NDI) eligibility per active
- European Union food supplement notification documentation (per country, as required)
Section VIIAggressive 30-Day Production Timeline
We are compressing the production timeline to 30 days from this RFQ to mass production. Please confirm your factory can meet this aggressive timeline. If the standard timeline at your factory is longer, please indicate what specific stage requires more time and propose realistic adjustments.
| Phase | Milestone | Target Duration |
|---|---|---|
| Week 1 | Receive written quote + answered questions + 50-bottle sample per SKU (4 SKUs = 200 bottles total) for sensory verification | 7 days |
| Week 2 | Sensory testing on our side · approve/iterate flavor + texture · sign mass production order | 7 days |
| Week 3 | Mass production run: ~10,000 Core (split 2 flavors) + ~3,000 Pro (split 2 flavors) = ~13,000 bottles total · in-line QA | 7 days |
| Week 4 | Final QA + packaging + air freight to US 3PL warehouse | 7 days |
Total: 4 weeks (30 days) from this RFQ to first commercial inventory landed at the US warehouse. First DTC sale fires end of Month 1.
This timeline assumes (a) all imported patented ingredients (Berbevis®, Affron®, KSM-66®, MenaQ7®, Quatrefolic®, Cinnulin PF®) can be pre-ordered Week 1 in parallel with sample production, (b) sensory sample iteration completes in a single round, and (c) your factory has open production-line capacity. Please confirm feasibility or counter-propose with the fastest realistic timeline your factory can commit to.
Section VIIINext Steps
If your factory can fully or partially deliver this product, please send us:
- Your written answers to the ten questions above
- An initial price quote — rough estimate is acceptable, we can refine later
- A sample of your closest existing gummy products (specifically NFC Lemon Juice Vitamin C Pectin Gummy + Probiotic Prebiotic Pectin Gummy) so we can verify base manufacturing quality before pilot
We're looking forward to building this partnership. Thank you for the detailed Mengxiaotai product card — your Tongnan lemon vertical is exactly the foundation we want for this product.
With kind regards,
中文版本 · Chinese Version
杨女士您好，
我们正在为美国 + 欧盟市场开发一款女性高端健康营养软糖 — SHIFT 45+ Max。产品面向 45 岁以上、正经历围绝经期 / 绝经期过渡的女性。
在仔细研究贵公司"檬小泰"的完整产品体系后，我们已选择貴厂作为首选制造合作伙伴。贵厂与铜南柠檬 (世界三大顶级柠檬产区之一) 的垂直整合，是亚洲任何其他供应商无法匹及的产品基础。
我们将以同一产品线下的两个变体上市 — SHIFT 45+ Core (每天 2 粒，大众市场漏斗) 与 SHIFT 45+ Pro (每天 3 粒，完整临床剂量，面向高端用户)。两个变体共享相同的口味方案和相同的核心成分 — 仅在部分辅助成分的剂量上有所不同。下方是完整双变体规格 + 10 个关键问题。
第一节项目总览 · 双 SKU 变体
| 项目 | SHIFT 45+ Core | SHIFT 45+ Pro |
|---|---|---|
| 品牌方 | Sunside Sdn Bhd (马来西亚) | |
| 目标市场 | 美国 + 欧盟 (45 岁以上女性，围绝经期 / 绝经期) | |
| 剂型 | 素食果胶软糖 | |
| 每日服用量 | 每天 2 粒 (早餐时一起服) | 每天 3 粒 (早 2 粒 + 晚 1 粒) |
| 瓶装规格 | 60 × 2g = 120g / 瓶 | 90 × 2g = 180g / 瓶 |
| 供应周期 | 30 天 | 30 天 |
| 目标零售价 (美元) | $69 (订阅 $55) | $89 (订阅 $71) |
| 定位 | 大众市场日常健康 | 完整临床剂量高端层 |
| 销量占比 (第一年) | ~75% 总销量 | ~25% 总销量 |
| 口味数量 | 两个变体均提供 2 个口味: 柠檬姜素食 · 柠檬蓝莓 | |
| 过敏原要求 | 纯素 无大豆 无麸质 无乳 无蜂蜜 非转基因 | |
| 保质期目标 | 25°C / 60%RH 条件下至少 18 个月 | |
| 年度采购量 | 第一年约 25,000 瓶 · 第二年约 60,000 瓶 | 第一年约 8,000 瓶 · 第二年约 20,000 瓶 |
第二节完整配方 Core (2 粒) 与 Pro (3 粒) 变体对比
两个变体共享相同的 19 种功能性成分。差异主要集中在肌醇这一体积最大的成分上，以及三种辅助成分 (桂皮、EGCG、镁)，Pro 变体恢复完整临床 RCT 剂量。请确认每种成分的采购能力和单价。
A. 核心明星成分 (临床试验剂量匹配 — 两个变体相同)
| # | 成分 | Core (2G) | Pro (3G) | 必需来源 / 专利 |
|---|---|---|---|---|
| i | 小檗碱磷脂复合物 | 1,100 mg | 1,100 mg | 意大利 Indena Berbevis® — 必需指定专利 |
| ii | 来自葛根的 S-equol | 10 mg | 10 mg | 葛根经 Lactococcus 20-92 菌株发酵 — 必需非大豆 |
| iii | 肌醇 | 300 mg D-chiro | 2,000 mg myo+d-chiro 40:1 | 药用级 · Pro 恢复完整 PCOS 级剂量 |
| iv | 藏红花提取物 | 28 mg | 28 mg | 西班牙 Pharmactive Affron® — 必需指定专利 |
| v | 南非醉茄根提取物 | 100 mg | 100 mg | 印度 Ixoreal KSM-66® — 必需指定专利 |
| vi | α-硫辛酸 (R-ALA 优先) | 200 mg | 200 mg | 稳定性问题 — 详见 Q7 |
B. 代谢与结构支持
| # | 成分 | Core (2G) | Pro (3G) | 来源 |
|---|---|---|---|---|
| vii | 苹果醋粉 | 500 mg | 500 mg | Bragg 同等品质，5% 乙酸 |
| viii | 锡兰桂皮提取物 (低香豆素) | 150 mg | 200 mg | Sabinsa Cinnulin PF® |
| ix | EGCG (脱咖啡因绿茶) | 100 mg | 200 mg | Taiyo Sunphenon® 90DCF |
| x | 吡啶甲酸铬 | 200 mcg | 200 mcg | Nutrition 21 Chromax® |
| xi | 维生素 D3 (胆钙化醇) | 2,000 IU | 2,000 IU | DSM Quali-D® |
| xii | 维生素 K2 MK-7 | 90 mcg | 90 mcg | NattoPharma MenaQ7® |
| xiii | 甘氨酸镁 (元素镁) | 75 mg | 100 mg | Albion TRAACS® |
| xiv | 维生素 B6 (P-5-P 活性形式) | 5 mg | 5 mg | 活性磷酸吡哆醛 |
| xv | 5-甲基四氢叶酸 | 400 mcg DFE | 400 mcg DFE | Gnosis Quatrefolic® |
C. 檬泰独家成分 (贵厂现有能力 — 两个变体相同)
| # | 成分 | Core (2G) | Pro (3G) | 说明 |
|---|---|---|---|---|
| xvi | 12 株专利益生菌 | 50 亿 CFU | 50 亿 CFU | 贵厂果胶包衣 FoodTalksTop30 菌株 (98% 肠道存活)。请推荐针对 45+ 围绝经期女性最佳的 1-3 株菌组合。 |
| xvii | 柠檬果胶益生元 | 200 mg | 200 mg | 贵厂专利柠檬果胶益生元技术 |
| xviii | 天然食用柠檬精油 | 30 mg | 30 mg | 贵厂中国独家食用柠檬油生产许可 — 定位为"铜南风土标识" |
| xix | 维生素 C (来自铜南 NFC 柠檬汁) | 100 mg | 100 mg | 来自贵厂现有铜南柠檬来源 |
D. Pro 独家差异化成分 (仅 Pro 变体 — 美容 + 热潮红增强)
| # | 成分 | Core (2G) | Pro (3G) | 必需来源 |
|---|---|---|---|---|
| xx | 发酵米糠提取物 (γ-谷维素 ≥10%) | — | 200 mg | 优先采用日本 Tsuno PeptiBalance® 或 OryzaPlus®。如难以采购，请提议贵厂自有发酵米糠 (酵母或乳酸菌发酵) — 详见问题 1 关于采购方案。 |
Pro 独家添加理由: 发酵米糠提取物添加三种已记录机制 — γ-谷维素 (日本 Foshu 批准的更年期热潮红声明，与我们的 S-equol 叠加)、GABA (与 KSM-66 + 藏红花协同助眠)、生育三烯酚 / 阿魏酸 (用于"由内而外美容"定位的皮肤弹性)。这是客户从 Core 升级到 Pro 的核心理由。
Core (2 × 2g 软糖): 有效成分总质量约 3.1 g — 每粒约 1.55 g 有效成分
Pro (3 × 2g 软糖): 有效成分总质量约 5.0 g — 每粒约 1.67 g 有效成分 (含 200mg 发酵米糠)
两者皆为高负载果胶配方。可行性请在下方 Q5 中确认。
D. 基质 (贵厂标准，含修改)
- 凝胶基底: 柠檬果胶 (主) + 卡拉胶 (副)
- 甜味剂: 甜菊糖苷 (Reb-M 发酵法) + 罗汉果苷 + 少量阿洛酮糖 — 请减少贵厂标准配方中麦芽糖醇 + 海藻糖用量，目标每份糖分 ≤ 2g
- 酸味剂: 柠檬酸 + 柠檬酸钠
- 脂溶性载体: 葵花卵磷脂 + MCT 油 (D3、K2、EGCG、ALA 输送载体)
- 涂层: 巴西棕榈蜡哑光面
- 色素: 仅天然来源 — 姜黄 + 红椒油树脂 (柠檬姜) 或天然花青素 (柠檬蓝莓)
- 严格不含: 蜂蜜、明胶、大豆蛋白、人工色素、人工香料、蔗糖、麸质、乳制品
第三节两种口味方案
第四节包装要求
| 项目 | Core (2G) | Pro (3G) |
|---|---|---|
| 瓶装 | HDPE 哑光 120g (60 × 2g) | HDPE 哑光 180g (90 × 2g) — 定制 |
| 高端升级选项 | 标准 HDPE | 第二年可升级为玻璃琥珀瓶 |
| SKU 总数 | 共 4 个 SKU = 2 个变体 × 2 个口味 (Core 柠檬姜 · Core 柠檬蓝莓 · Pro 柠檬姜 · Pro 柠檬蓝莓) | |
| 通用要求 | 防拆封封口 · 干燥剂 · 出口标签 (美国英文营养成分表 + 欧盟食品补充剂合规声明) · 每个 SKU 独立标签设计 | |
第五节10 个关键问题
请在回复中逐一答复以下问题。这些答复决定了生产可行性、时间表和价格。
进口专利成分采购
贵厂能否进口并在我们的定制 OEM 批次中使用以下 7 种指定专利成分?
- Indena Berbevis® (意大利)
- Pharmactive Affron® (西班牙)
- Ixoreal KSM-66® (印度)
- NattoPharma MenaQ7® (挪威)
- Gnosis Quatrefolic® (意大利)
- Sabinsa Cinnulin PF® (印度 / 美国)
- Tsuno PeptiBalance® 或 OryzaPlus® — 发酵米糠提取物 (日本，仅 Pro 变体)
如可以，请告知每公斤或每单位价格，以及供应商端的最低采购量。
关于日本 Tsuno 具体而言: 如直接进口困难，贵厂能否提议自有发酵米糠提取物 (酵母或乳酸菌发酵，标准化 γ-谷维素 ≥10%)? 贵厂现有的发酵基础设施 (益生菌 + 柠檬果胶) 表明这在贵厂能力范围内。请告知 Tsuno 进口与贵厂自有发酵的成本差。
葛根 S-equol 发酵
贵厂能否使用 Lactococcus 20-92 菌株 (类似大塚 Otsuka SE5-OH 工艺) 发酵葛根 (Pueraria lobata) 提取物，生产每份 10 mg 的 S-equol?
如贵厂没有此发酵能力，能否通过授权供应商采购 SE5-OH 成分? 这是最关键的成分 — 非大豆来源的 S-equol 是本产品的核心品牌差异化。
益生菌菌株推荐
在贵厂 12 种专利 FoodTalksTop30 菌株中，哪 1-3 株菌对 45+ 围绝经期女性"肠-免疫-代谢"交叉作用证据最充分? 请提供菌株名称和推荐 CFU 剂量分配。我们目标是每份共计 50 亿 CFU。
肌醇 40:1 比例 2g 剂量
贵厂能否采购药用级肌醇，精确按 40:1 myo / d-chiro 比例配置，每份 2,000 mg? 这是配方中体积最大的单一有效成分。
两个变体的高负载软糖容量
两个变体均为高负载果胶配方:
- Core: 每 2g 软糖约 1.55 g 有效成分 (78% 负载)
- Pro: 每 2g 软糖约 1.60 g 有效成分 (80% 负载)
贵厂高负载果胶软糖技术能否同时达到两个密度? 如否，请提议最接近的可行配方。
两个瓶装规格
我们需要贵厂生产两个瓶装 SKU: Core 为 120g (60 × 2g — 贵厂标准) 和 Pro 为 180g (90 × 2g — 定制)。180g 瓶在贵厂生产线上可行吗? 与贵厂 120g 标准瓶相比每瓶成本差?
α-硫辛酸 (ALA) 稳定性
α-硫辛酸 200 mg 在果胶软糖基质中 18 个月保质期内可能存在硫味和稳定性问题。贵厂是否处理过 ALA 在软糖中的应用? 优先形式 (R-ALA 与外消旋) 或需要微胶囊化吗?
CoA 分析证书文件
请确认贵厂能为每批次的每种有效成分提供第三方分析证书 (CoA)，涵盖:
- 鉴定 (HPLC 用于植物，ICP-MS 用于矿物质)
- 纯度和重金属 (铅、砷、镉、汞 < EU/US 限量)
- 微生物学 (总菌落数、酵母 / 霉菌、致病菌)
- 有效物含量 (小檗碱百分比、异黄酮百分比等)
- 农药残留 (针对植物成分)
- 过敏原测试 (大豆 / 麸质 / 乳 / 坚果 < 检出限)
- 英文版 CoA
稳定性测试 (18 个月保质期)
我们要求在 25°C / 60%RH 储存条件下保质期 18 个月。请确认贵厂可以进行加速稳定性测试 (40°C / 75%RH × 6 个月) 来验证。关键参数: 益生菌 CFU 存活、维生素 D3 保留、K2 保留、ALA 稳定性。
价格、MOQ、交货时间 — Core 与 Pro 分别报价
请按美元 FOB 重庆报价，Core 与 Pro 分开每个批次大小。SKU 总数为 4 个 (2 个变体 × 2 个口味)。
(a) 感官样品 — 每 SKU 50 瓶 × 4 SKU = 共 200 瓶: 每 SKU 费用 + 交货时间?
(b) 试产批次 — 每 SKU 500 瓶 × 4 SKU = 共 2,000 瓶: 每瓶每 SKU 价格 + MOQ + 交货时间?
(c) 量产批次 — Core: 每口味 5,000-7,000 瓶 (共 10,000-14,000); Pro: 每口味 2,000-3,000 瓶 (共 4,000-6,000)。每瓶每 SKU 价格 + MOQ + 交货时间?
付款条款: 30% 定金 + 70% 出货前付清，或贵方标准条款?
第六节监管文件要求
请确认以下文件可用性:
- ISO 9001 + ISO 22000 + HACCP + GMP 认证
- 中国食品生产许可 (SC 证)
- 美国 + 欧盟出口许可证
- 素食认证 (或愿意申请认证)
- 非转基因项目兼容性，犹太洁食 / 清真资质 (美国零售优先犹太洁食)
- 1 年期美国 FDA 新膳食成分 (NDI) 资格文件 (每个有效成分)
- 欧盟食品补充剂通报文件 (如需按国家)
第七节30 天加速生产时间表
我们将生产时间表压缩为从本 RFQ 到量产 30 天。请确认贵厂能否达到此加速时间表。如贵厂标准时间表更长，请指明具体哪个阶段需要更多时间，并提出实际的调整方案。
| 阶段 | 里程碑 | 目标时长 |
|---|---|---|
| 第 1 周 | 收到贵厂书面报价 + 问题答复 + 每 SKU 50 瓶样品 (共 4 SKU = 200 瓶) 用于感官验证 | 7 天 |
| 第 2 周 | 我方感官测试 · 批准 / 调整口味与质地 · 签量产订单 | 7 天 |
| 第 3 周 | 量产批生产: 约 10,000 瓶 Core (分 2 口味) + 约 3,000 瓶 Pro (分 2 口味) = 共约 13,000 瓶 · 在线 QA | 7 天 |
| 第 4 周 | 最终 QA + 包装 + 空运至美国 3PL 仓库 | 7 天 |
总计: 4 周 (30 天)从本 RFQ 到首批商业库存到达美国仓库。Month 1 月底首次 DTC 销售。
此时间表假设: (a) 所有进口专利成分 (Berbevis®, Affron®, KSM-66®, MenaQ7®, Quatrefolic®, Cinnulin PF®) 可在第 1 周与样品生产并行预订, (b) 感官样品迭代单轮完成, (c) 贵厂有开放的生产线产能。请确认可行性，或反提议贵厂能承诺的最快实际时间表。
第八节下一步
如贵厂能完全或部分交付本产品，请发送以下内容:
- 上述 10 个问题的书面答复
- 初步报价 (粗略估算即可，后续可细化)
- 贵厂现有最接近的软糖产品样品 (具体: NFC 柠檬汁维生素 C 果胶软糖 + 益生菌益生元果胶软糖)，以便我们在承诺试产前验证贵厂基础生产质量
期待与贵厂建立长期合作伙伴关系。再次感谢贵公司提供的詳細"檬小泰"产品资料 — 贵厂的铜南柠檬垂直产业链正是我们想要的产品基础。
此致敬礼